Epigenetic regulation in mammalian preimplantation embryo development
نویسندگان
چکیده
منابع مشابه
Epigenetic regulation in mammalian preimplantation embryo development
Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significant changes. Each preimplantation embryo stage has its own characteristic epige...
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Abbreviations: PGCs: Primordial Germ Cells; XCI: X Chromosome Inactivation; 5mC: 5-methylcytosine; 5hmC: 5-hydroxymethylcytosine; Xp: Paternal X Chromosome; 5fC: 5-formylcytosine; 5caC: 5-carboxylcytosine; ICM: Inner Cell Mass; PRC2: Polycomb Repressive Complex 2; IAPs: Intracisternal-A-Particles; CGIs: CpG Islands; gDMRs: Germline Differently Methylated Regions; Xi: Inactive X Chromosome; qRT-...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2009
ISSN: 1477-7827
DOI: 10.1186/1477-7827-7-59